Hi all

Quick followup with some extra thoughts. I am not confident whether I will get a reply. However my query is genuine, informed, and I believe of genuine merit. As always we can run into respect issues. I believe on this matter at least I can argue considerable credentials. I feel I have a right to ask them too because I am facing so many obstacles on the matter. Hypothetically, despite many obstacles, I could easily be about to step in front of a judge very soon and need an expert on the matter

A few extra thoughts though. Obviously detecting such effects using many methods could be theoretically or practically impossible, that is assuming small but highly devastating effects. Requirements for number and detail of records and cases across multiple populations, and possibly generations.

There are usually many ways to approach such analyses though and I imagine there could be some much simpler approaches using mass data (eg prescriptions) across multiple populations, either as individuals, or even aggregated, provided there were ways to compare different attributes of said populations. eg Comparison of the trajectories of certain prescription types, and certain disorders, compared across countries or continents etc

I would be genuinely grateful for people working in, or who can refer to such studies, at such a scale.

Under different circumstances I would even try connecting with a school to do a research project. The practicalities of that are too much of a burden too at the moment

However, I believe there would be more than enough evidence of many kinds, and justification of the terrible outcomes from such risks (even with small effect sizes) to justify such a study before any ethics committee. I believe sometimes truth requires some people to risk so-called disrespect. I believe I am being completely respectful in every way, especially to science and knowledge and research and professions. So respectful I ask all those channels for assistance